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type="integer"> 0 </cn> </apply> <apply> <eq/> <ci> PI3KAkt_M </ci> <cn type="integer"> 0 </cn> </apply> <apply> <eq/> <ci> TLRs_M </ci> <cn type="integer"> 1 </cn> </apply> </apply> <apply> <and/> <apply> <eq/> <ci> ERK_M </ci> <cn type="integer"> 0 </cn> </apply> <apply> <eq/> <ci> PI3KAkt_M </ci> <cn type="integer"> 1 </cn> </apply> <apply> <eq/> <ci> TLRs_M </ci> <cn type="integer"> 0 </cn> </apply> <apply> <eq/> <ci> IL1 </ci> <cn type="integer"> 1 </cn> </apply> </apply> <apply> <and/> <apply> <eq/> <ci> ERK_M </ci> <cn type="integer"> 0 </cn> </apply> <apply> <eq/> <ci> PI3KAkt_M </ci> <cn type="integer"> 1 </cn> </apply> <apply> <eq/> <ci> TLRs_M </ci> <cn type="integer"> 1 </cn> </apply> </apply> <apply> <and/> <apply> <eq/> <ci> ERK_M </ci> <cn type="integer"> 1 </cn> </apply> <apply> <eq/> <ci> ROS_M </ci> <cn type="integer"> 0 </cn> </apply> <apply> <eq/> <ci> PI3KAkt_M </ci> <cn type="integer"> 0 </cn> </apply> <apply> <eq/> <ci> TLRs_M </ci> <cn type="integer"> 1 </cn> </apply> </apply> <apply> <and/> <apply> <eq/> <ci> ERK_M </ci> <cn type="integer"> 1 </cn> </apply> <apply> <eq/> <ci> ROS_M </ci> <cn type="integer"> 0 </cn> </apply> <apply> <eq/> <ci> PI3KAkt_M </ci> <cn type="integer"> 1 </cn> </apply> <apply> <eq/> <ci> TLRs_M </ci> <cn type="integer"> 0 </cn> </apply> <apply> <eq/> <ci> IL1 </ci> <cn type="integer"> 1 </cn> </apply> </apply> <apply> <and/> <apply> <eq/> <ci> ERK_M </ci> <cn type="integer"> 1 </cn> </apply> <apply> <eq/> <ci> ROS_M </ci> <cn type="integer"> 0 </cn> </apply> <apply> <eq/> <ci> PI3KAkt_M </ci> <cn type="integer"> 1 </cn> </apply> <apply> <eq/> <ci> TLRs_M </ci> <cn type="integer"> 1 </cn> </apply> </apply> <apply> <and/> <apply> <eq/> <ci> ERK_M </ci> <cn type="integer"> 1 </cn> </apply> <apply> <eq/> <ci> ROS_M </ci> <cn type="integer"> 1 </cn> </apply> </apply> </apply> </math> </qual:functionTerm> </qual:listOfFunctionTerms> </qual:transition> <qual:transition qual:id="tr_ROS_M"> <qual:listOfInputs> <qual:input qual:qualitativeSpecies="FoxO3a_M" qual:transitionEffect="none" qual:sign="negative" qual:id="tr_ROS_M_in_16"/> <qual:input qual:qualitativeSpecies="TLRs_M" qual:transitionEffect="none" qual:sign="positive" qual:id="tr_ROS_M_in_21"/> <qual:input qual:qualitativeSpecies="IL1" qual:transitionEffect="none" qual:sign="positive" qual:id="tr_ROS_M_in_24"/> </qual:listOfInputs> <qual:listOfOutputs> <qual:output qual:qualitativeSpecies="ROS_M" qual:transitionEffect="assignmentLevel" qual:id="tr_ROS_M_out"/> </qual:listOfOutputs> <qual:listOfFunctionTerms> <qual:defaultTerm qual:resultLevel="0"> </qual:defaultTerm> <qual:functionTerm qual:resultLevel="1"> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <and/> <apply> <eq/> <ci> FoxO3a_M </ci> <cn type="integer"> 0 </cn> </apply> <apply> <eq/> <ci> TLRs_M </ci> <cn type="integer"> 1 </cn> </apply> <apply> <eq/> <ci> IL1 </ci> <cn type="integer"> 1 </cn> </apply> </apply> </math> </qual:functionTerm> </qual:listOfFunctionTerms> </qual:transition> <qual:transition qual:id="tr_PI3KAkt_M"> <qual:listOfInputs> <qual:input qual:qualitativeSpecies="ROS_M" qual:transitionEffect="none" qual:sign="positive" qual:id="tr_PI3KAkt_M_in_19"/> <qual:input qual:qualitativeSpecies="TLRs_M" qual:transitionEffect="none" qual:sign="positive" qual:id="tr_PI3KAkt_M_in_21"/> <qual:input qual:qualitativeSpecies="GCSF" qual:transitionEffect="none" qual:sign="positive" qual:id="tr_PI3KAkt_M_in_25"/> </qual:listOfInputs> <qual:listOfOutputs> <qual:output qual:qualitativeSpecies="PI3KAkt_M" qual:transitionEffect="assignmentLevel" qual:id="tr_PI3KAkt_M_out"/> </qual:listOfOutputs> <qual:listOfFunctionTerms> <qual:defaultTerm qual:resultLevel="0"> </qual:defaultTerm> <qual:functionTerm qual:resultLevel="1"> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <or/> <apply> <and/> <apply> <eq/> <ci> ROS_M </ci> <cn type="integer"> 0 </cn> </apply> <apply> <eq/> <ci> TLRs_M </ci> <cn type="integer"> 0 </cn> </apply> <apply> <eq/> <ci> GCSF </ci> <cn type="integer"> 1 </cn> </apply> </apply> <apply> <and/> <apply> <eq/> <ci> ROS_M </ci> <cn type="integer"> 0 </cn> </apply> <apply> <eq/> <ci> TLRs_M </ci> <cn type="integer"> 1 </cn> </apply> </apply> <apply> <eq/> <ci> ROS_M </ci> <cn type="integer"> 1 </cn> </apply> </apply> </math> </qual:functionTerm> </qual:listOfFunctionTerms> </qual:transition> <qual:transition qual:id="tr_TLRs_M"> <qual:listOfInputs> <qual:input qual:qualitativeSpecies="lTLR" qual:transitionEffect="none" qual:sign="positive" qual:id="tr_TLRs_M_in_23"/> </qual:listOfInputs> <qual:listOfOutputs> <qual:output qual:qualitativeSpecies="TLRs_M" qual:transitionEffect="assignmentLevel" qual:id="tr_TLRs_M_out"/> </qual:listOfOutputs> <qual:listOfFunctionTerms> <qual:defaultTerm qual:resultLevel="0"> </qual:defaultTerm> <qual:functionTerm qual:resultLevel="1"> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <eq/> <ci> lTLR </ci> <cn type="integer"> 1 </cn> </apply> </math> </qual:functionTerm> </qual:listOfFunctionTerms> </qual:transition> <qual:transition qual:id="tr_VCAM1_M"> <qual:listOfInputs> <qual:input qual:qualitativeSpecies="Bcatenin_M" qual:transitionEffect="none" qual:sign="negative" qual:id="tr_VCAM1_M_in_13"/> <qual:input qual:qualitativeSpecies="NfkB_M" qual:transitionEffect="none" qual:sign="positive" qual:id="tr_VCAM1_M_in_18"/> <qual:input qual:qualitativeSpecies="PI3KAkt_M" qual:transitionEffect="none" qual:sign="positive" qual:id="tr_VCAM1_M_in_20"/> </qual:listOfInputs> <qual:listOfOutputs> <qual:output qual:qualitativeSpecies="VCAM1_M" qual:transitionEffect="assignmentLevel" qual:id="tr_VCAM1_M_out"/> </qual:listOfOutputs> <qual:listOfFunctionTerms> <qual:defaultTerm qual:resultLevel="0"> </qual:defaultTerm> <qual:functionTerm qual:resultLevel="1"> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <or/> <apply> <eq/> <ci> Bcatenin_M </ci> <cn type="integer"> 0 </cn> </apply> <apply> <and/> <apply> <eq/> <ci> Bcatenin_M </ci> <cn type="integer"> 1 </cn> </apply> <apply> <eq/> <ci> NfkB_M </ci> <cn type="integer"> 0 </cn> </apply> <apply> <eq/> <ci> PI3KAkt_M </ci> <cn type="integer"> 1 </cn> </apply> </apply> <apply> <and/> <apply> <eq/> <ci> Bcatenin_M </ci> <cn type="integer"> 1 </cn> </apply> <apply> <eq/> <ci> NfkB_M </ci> <cn type="integer"> 1 </cn> </apply> </apply> </apply> </math> </qual:functionTerm> </qual:listOfFunctionTerms> </qual:transition> <qual:transition qual:id="tr_IL1"> <qual:listOfInputs> <qual:input qual:qualitativeSpecies="NfkB_H" qual:transitionEffect="none" qual:sign="positive" qual:id="tr_IL1_in_7"/> <qual:input qual:qualitativeSpecies="PI3KAkt_H" qual:transitionEffect="none" qual:sign="negative" qual:id="tr_IL1_in_8"/> <qual:input qual:qualitativeSpecies="ROS_H" qual:transitionEffect="none" qual:sign="positive" qual:id="tr_IL1_in_9"/> <qual:input qual:qualitativeSpecies="NfkB_M" qual:transitionEffect="none" qual:sign="positive" qual:id="tr_IL1_in_18"/> <qual:input qual:qualitativeSpecies="ROS_M" qual:transitionEffect="none" qual:sign="positive" qual:id="tr_IL1_in_19"/> <qual:input qual:qualitativeSpecies="PI3KAkt_M" qual:transitionEffect="none" qual:sign="negative" qual:id="tr_IL1_in_20"/> </qual:listOfInputs> <qual:listOfOutputs> <qual:output qual:qualitativeSpecies="IL1" qual:transitionEffect="assignmentLevel" qual:id="tr_IL1_out"/> </qual:listOfOutputs> <qual:listOfFunctionTerms> <qual:defaultTerm qual:resultLevel="0"> </qual:defaultTerm> <qual:functionTerm qual:resultLevel="1"> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <or/> <apply> <and/> <apply> <eq/> <ci> NfkB_H </ci> <cn type="integer"> 0 </cn> </apply> <apply> <eq/> <ci> PI3KAkt_H </ci> <cn type="integer"> 0 </cn> </apply> <apply> <eq/> <ci> ROS_H </ci> <cn type="integer"> 0 </cn> </apply> <apply> <eq/> <ci> NfkB_M </ci> <cn type="integer"> 0 </cn> </apply> <apply> <eq/> <ci> ROS_M </ci> <cn type="integer"> 1 </cn> </apply> <apply> <eq/> <ci> PI3KAkt_M </ci> <cn type="integer"> 0 </cn> </apply> </apply> <apply> <and/> <apply> <eq/> <ci> NfkB_H </ci> <cn type="integer"> 0 </cn> </apply> <apply> <eq/> <ci> PI3KAkt_H </ci> <cn type="integer"> 0 </cn> </apply> <apply> <eq/> <ci> ROS_H </ci> <cn type="integer"> 0 </cn> </apply> <apply> <eq/> <ci> NfkB_M </ci> <cn type="integer"> 1 </cn> </apply> <apply> <eq/> <ci> PI3KAkt_M </ci> <cn type="integer"> 0 </cn> </apply> </apply> <apply> <and/> <apply> <eq/> <ci> NfkB_H </ci> <cn type="integer"> 0 </cn> </apply> <apply> <eq/> <ci> PI3KAkt_H </ci> <cn type="integer"> 0 </cn> </apply> <apply> <eq/> <ci> ROS_H </ci> <cn type="integer"> 1 </cn> </apply> </apply> <apply> <and/> <apply> <eq/> <ci> NfkB_H </ci> <cn type="integer"> 0 </cn> </apply> <apply> <eq/> <ci> PI3KAkt_H </ci> <cn type="integer"> 1 </cn> </apply> <apply> <eq/> <ci> NfkB_M </ci> <cn type="integer"> 0 </cn> </apply> <apply> <eq/> <ci> ROS_M </ci> <cn type="integer"> 1 </cn> </apply> <apply> <eq/> <ci> PI3KAkt_M </ci> <cn type="integer"> 0 </cn> </apply> </apply> <apply> <and/> <apply> <eq/> <ci> NfkB_H </ci> <cn type="integer"> 0 </cn> </apply> <apply> <eq/> <ci> PI3KAkt_H </ci> <cn type="integer"> 1 </cn> </apply> <apply> <eq/> <ci> NfkB_M </ci> <cn type="integer"> 1 </cn> </apply> <apply> <eq/> <ci> PI3KAkt_M </ci> <cn type="integer"> 0 </cn> </apply> </apply> <apply> <and/> <apply> <eq/> <ci> NfkB_H </ci> <cn type="integer"> 1 </cn> </apply> <apply> <eq/> <ci> PI3KAkt_H </ci> <cn type="integer"> 0 </cn> </apply> </apply> <apply> <and/> <apply> <eq/> <ci> NfkB_H </ci> <cn type="integer"> 1 </cn> </apply> <apply> <eq/> <ci> PI3KAkt_H </ci> <cn type="integer"> 1 </cn> </apply> <apply> <eq/> <ci> NfkB_M </ci> <cn type="integer"> 0 </cn> </apply> <apply> <eq/> <ci> ROS_M </ci> <cn type="integer"> 1 </cn> </apply> <apply> <eq/> <ci> PI3KAkt_M </ci> <cn type="integer"> 0 </cn> </apply> </apply> <apply> <and/> <apply> <eq/> <ci> NfkB_H </ci> <cn type="integer"> 1 </cn> </apply> <apply> <eq/> <ci> PI3KAkt_H </ci> <cn type="integer"> 1 </cn> </apply> <apply> <eq/> <ci> NfkB_M </ci> <cn type="integer"> 1 </cn> </apply> <apply> <eq/> <ci> PI3KAkt_M </ci> <cn type="integer"> 0 </cn> </apply> </apply> </apply> </math> </qual:functionTerm> </qual:listOfFunctionTerms> </qual:transition> <qual:transition qual:id="tr_GCSF"> <qual:listOfInputs> <qual:input qual:qualitativeSpecies="IL1" qual:transitionEffect="none" qual:sign="positive" qual:id="tr_GCSF_in_24"/> </qual:listOfInputs> <qual:listOfOutputs> <qual:output qual:qualitativeSpecies="GCSF" qual:transitionEffect="assignmentLevel" qual:id="tr_GCSF_out"/> </qual:listOfOutputs> <qual:listOfFunctionTerms> <qual:defaultTerm qual:resultLevel="0"> </qual:defaultTerm> <qual:functionTerm qual:resultLevel="1"> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <eq/> <ci> IL1 </ci> <cn type="integer"> 1 </cn> </apply> </math> </qual:functionTerm> </qual:listOfFunctionTerms> </qual:transition> </qual:listOfTransitions> <listOfCompartments> <compartment constant="true" id="comp1"/> </listOfCompartments> </model> </sbml>